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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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UK-101 is a selective small-molecule inhibitor of the immunoproteasome β1i (LMP2) subunit used in biochemical and cellular research to probe immunoproteasome function and induce apoptosis in certain cancer models.
Selective LMP2 (β1i) inhibitor with reported IC50 of 104 nM.
Shows ~144-fold selectivity versus β1c and ~10-fold versus β5.
High reported purity (99.58%) suitable for research applications.
Molecular weight 484.74 g·mol⁻¹ and formula C25H48N2O5Si.
Soluble in DMSO and supplied in small research quantities, including 1 mg packs.
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dCTP PCR Grade is a 100 mM clear colorless SOLUTIONon of the sodium salt (pH 8.3). PCR Grade nucleotides from Roche are specially manufactured and purified to the highest possible chemical purity. PCR Grade nucleotides contain at least 99% of the relevant deoxynucleoside-triphosphate (dNTP) and less than 0.9% deoxynucleoside-diphosphate (dNDP).
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